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LAMP3 is involved in tamoxifen resistance in breast cancer cells through the modulation of autophagy

✍ Scribed by Nagelkerke, A.; Sieuwerts, A. M.; Bussink, J.; Sweep, F. C. G. J.; Look, M. P.; Foekens, J. A.; Martens, J. W. M.; Span, P. N.

Book ID
126577309
Publisher
Bioscientifica
Year
2014
Tongue
English
Weight
371 KB
Volume
21
Category
Article
ISSN
1351-0088

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## Abstract Receptor tyrosine kinase activity is essential for erbB2 (HER2/__neu__) promotion of breast carcinogenesis, metastasis and therapeutic resistance. erbB2 kinase can be activated by dimerization with another erbB receptor, most of which bind ligands. Of these, the erbB2/erbB3 heterodimer