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Lamotrigine possibly linked to cleft palate/lip, warns FDA

Book ID
120850373
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2006
Weight
138 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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X-linked mental retardation associated w
X-linked mental retardation associated with cleft lip/palate maps to Xp11.3-q21.3
โœ Siderius, Liesbeth E.; Hamel, Ben C.J.; van Bokhoven, Hans; de Jager, Frank; van ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 46 KB ๐Ÿ‘ 1 views

A family is described in which X-linked mild to borderline mental retardation (MR) is associated with cleft lip/palate. Linkage analysis showed a maximum LOD score of Z=2.78 at =0.0 for the DXS441 locus with flanking markers DXS337 and DXS990, defining the region Xp11.3-q21.3 with a linkage interval