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Lamotrigine increases intracellular Ca 2+ levels and Ca 2+ /calmodulin-dependent kinase II activation in mouse dorsal root ganglion neurones

โœ Scribed by Lee, E. S.; Ryu, J. H.; Kim, E.-J.; Kim, G.-T.; Cho, Y.-W.; Park, H.-J.; Tak, H.-M.; Han, J.; Kang, D.


Book ID
119826611
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
383 KB
Volume
207
Category
Article
ISSN
1748-1708

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## Abstract Spiral ganglion neuron (SGN) survival in vitro can be maintained by neurotrophins, permeant cAMP analogs, and depolarization in an additive manner, with depolarization being the most efficacious. Therefore, we used cultured SGNs to determine the mechanism by which depolarization promote