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Lamivudine monotherapy for spontaneous severe acute exacerbation of chronic hepatitis B

✍ Scribed by AKIHITO TSUBOTA; YASUJI ARASE; YOSHIYUKI SUZUKI; FUMITAKA SUZUKI; HITOMI SEZAKI; TETSUYA HOSAKA; NORIO AKUTA; TAKASHI SOMEYA; MASAHIRO KOBAYASHI; SATOSHI SAITOH; KENJI IKEDA; HIROMITSU KUMADA

Book ID: 108949988
Publisher: John Wiley and Sons
Year: 2005
Tongue: English
Weight: 99 KB
Volume: 20
Category: Article
ISSN: 0815-9319
DOI: 10.1111/j.1440-1746.2004.03534.x

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## Abstract The pretherapy factors that could influence the emergence of resistant hepatitis B virus (HBV) tyrosine‐methionine‐aspartate‐aspartate (YMDD) motif mutants against lamivudine are not fully known in prolonged lamivudine therapy for hepatitis B e antigen (HBeAg)‐positive chronic hepatitis