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Laminin affects polymerization, depolymerization and neurotoxicity of Aβ peptide

✍ Scribed by Carlos Morgan; Manuel P Bugueño; Jorge Garrido; Nibaldo C Inestrosa


Book ID
117408330
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
824 KB
Volume
23
Category
Article
ISSN
0196-9781

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## Abstract Alzheimer's disease (AD) is a neurodegenerative disease of the central nervous system characterized by two major lesions: extracellular senile plaques and intraneuronal neurofibrillary tangles. β‐Amyloid (Aβ) is known to play a major role in the pathogenesis of AD. Protein synthesis and