𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Lag phase model for transient growth of pseudomonas putida on phenol

✍ Scribed by Alireza Tarighian; Gordon Hill; Yen-Han Lin

Book ID
102805029
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
509 KB
Volume
79
Category
Article
ISSN
0008-4034

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✦ Synopsis

Abstract

The successful design of large‐scale bioreactors requires the ability to predict both steady‐state and dynamic operating conditions. At the same time, mathematical models should not be too complex in order to reduce experimental work required to determine kinetic parameters. A simple model which predicts the behaviour of batch and transient continuous culture operations is presented and experimentally verified. The model is based on two regions of metabolic activity: the lag phase and the active phase. Pseudomonas putida growing on phenol as a substrate in a well‐mixed bioreactor was tested in three modes of operation: batch, continuous start‐up and continuous step‐change. The model is demonstrated to predict all the qualitative aspects of the dynamic phases of growth and is quantitatively accurate.

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