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Lactosylated Chitosan for DNA Delivery into Hepatocytes: The Effect of Lactosylation on the Physicochemical Properties and Intracellular Trafficking of pDNA/Chitosan Complexes

✍ Scribed by Hashimoto, Mayu; Morimoto, Minoru; Saimoto, Hiroyuki; Shigemasa, Yoshihiro; Sato, Toshinori

Book ID
126182643
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
398 KB
Volume
17
Category
Article
ISSN
1043-1802

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## Abstract ## Background As we have previously shown that lactosylated polyethylenimine (PEI) is the most efficient glycosylated PEI for gene transfer into human airway epithelial cells in primary culture, we have studied here the role of the lactose residue in the enhancement of gene transfer ef