Lactic acidosis secondary to severe anemia in a patient with paroxysmal nocturnal hemoglobinuria
β Scribed by Essex, David W.; Jin, David K.; Bradley, Thomas P.
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 21 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0361-8609
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β¦ Synopsis
A patient with paroxysmal nocturnal hemoglobinuria developed lactic acidosis associated with severe anemia. The lactic acidosis corrected after blood transfusion. In the absence of shock, sepsis, or other identifiable causes of lactic acidosis, the severe anemia (hemoglobin 1.2 g/dl) appeared to be the primary etiologic factor. Am.
π SIMILAR VOLUMES
The relationships between paroxysmal nocturnal hemogloblnuria (PNH), aplastlc anemia (AA), and myelodysplastlc syndrome (MDS) are not clear. Here we describe a patient, J20, who developed a reciprocal translocation of chromosome 12 and PNH during follow-up of AA. All metaphases In CD59-deflcient bon