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Lactate involvement in neuron–glia metabolic interaction: 13C-NMR spectroscopy contribution

✍ Scribed by A.-K Bouzier-Sore; S Serres; P Canioni; M Merle


Book ID
116308225
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
235 KB
Volume
85
Category
Article
ISSN
0300-9084

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The metabolism of [U-13C]aspartate was studied in cultured cortical astrocytes and cerebellar granule neurons in the presence of glucose and during inhibition of glycolysis. Redissolved, lyophilized cell extracts and incubation media were analyzed by 13C nuclear magnetic resonance spectroscopy for t