## Abstract Excitotoxicity and cell death induced by glutamate are involved in many neurodegenerative disorders. We have previously demonstrated that excitotoxicity induced by millimolar concentrations of glutamate in hippocampal slices involves apoptotic features and glutamateโinduced glutamate re
โฆ LIBER โฆ
Lactate-induced translocation of GLUT1 and GLUT4 is not mediated by the phosphatidylinositol-3-kinase pathway in the rat heart
โ Scribed by Rodolfo A. Medina; Richard Southworth; William Fuller; Pamela B. Garlick
- Book ID
- 106067699
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 191 KB
- Volume
- 97
- Category
- Article
- ISSN
- 0300-8428
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## Abstract Guanosine has many trophic effects in the CNS, including the stimulation of neurotrophic factor synthesis and release by astrocytes, which protect neurons against excitotoxic death. Therefore, we questioned whether guanosine protected astrocytes against apoptosis induced by staurosporin