Lactate dehydrogenase in the synovial tissue in rheumatoid arthritis: Total activity and isoenzyme composition
β Scribed by Seppo Lindy; Jouni Uitto; Heikki Turto; Pentti Rokkanen; Kauko Vainio
- Book ID
- 115819063
- Publisher
- Elsevier Science
- Year
- 1971
- Tongue
- English
- Weight
- 324 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0009-8981
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Objective Rheumatoid arthritis (RA) is a chronic inflammatory disorder of unknown origin. Histone deacetylase (HDA) activity is considered to play a major role in the transcriptional regulation of proinflammatory genes. We undertook this study to investigate the balance of histone a
Synovial fluid (SF) and synovial tissue from 10 patients with juvenile rheumatoid arthritis were examined. The SFs were heterogeneous with respect to the degree of complement activation. Quantification of C3dg and the terminal complement complex revealed a positive correlation between activation of