✦ LIBER ✦

Lactate Biosensor Based on Hydrotalcite-Like Compounds: Performances and Application to Serum Samples

✍ Scribed by Irene Carpani; Lorella Guadagnini; Domenica Tonelli

Publisher: John Wiley and Sons
Year: 2009
Tongue: English
Weight: 214 KB
Volume: 21
Category: Article
ISSN: 1040-0397
DOI: 10.1002/elan.200900118

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A lactate biosensor based on lactate oxidase supported onto a hydrotalcite, electrochemically deposited on a platinum surface, was developed for the first time. For the best electrode configuration, a linear response up to 0.8 mM, with a limit of detection of 14 μM and a sensitivity of 91 mA M^−1^ cm^−2^, was obtained. The influence of some interferents due to the oxidation of hydrogen peroxide (at +0.35 V vs. SCE) was also studied. By controlling carefully the experimental conditions, the determination of lactate in a commercial serum sample in the presence of interferents was successfully accomplished.

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