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?-Lactam analogues of penicillanic and carbapenicillanic acids

✍ Scribed by Baldwin, Jack E.; Chan, Ming Fai; Gallacher, Gerard; Monk, Peter; Prout, Keith


Book ID
127310236
Publisher
The Royal Society of Chemistry
Year
1983
Tongue
English
Weight
235 KB
Volume
5
Category
Article
ISSN
0022-4936

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Stereoselective Syntheses of Tetrahydroe
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A total synthesis of the optically active tetrahydroesterastinB -1actam analogue 2 using MilZer's hydroxamate approach is described (Scheme 2). Significant modification of published procedures has resulted in a short and facile stereospecific preparation of the N-[(benzyloxycarbonyl)methyl]$ -1actam