Lacking exon5 of variant estrogen receptor in human breast cancer
β Scribed by Lei Zhang; Ping Gong; Sulian Sun; Zhiwei Dong
- Publisher
- Chinese Anti-Cancer Association
- Year
- 1998
- Tongue
- English
- Weight
- 223 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1000-9604
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Androgens and androgen receptor (AR) are involved in many regulatory processes in the growth of female breast cells. Mutations in the AR gene and/or alterations of the AR protein sequence may be related to the development and progression of breast cancer. Using reverse transcriptionpolymerase chain
We have carried out a quantitative analysis of ER-alpha and ER-beta mRNA expression in normal (n = 11) and breast cancer (n = 112) tissues using a real-time (Taq-Man) PCR assay. Expression of ER-beta mRNA variants has also been studied by triple-primer PCR assay. ER-alpha mRNA levels in normal breas