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Lack of tumor necrosis factor receptor type 1 inhibits liver fibrosis induced by carbon tetrachloride in mice

✍ Scribed by Kaori Sudo; Yasuhiro Yamada; Hisataka Moriwaki; Kuniaki Saito; Mitsuru Seishima

Book ID: 116397519
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 685 KB
Volume: 29
Category: Article
ISSN: 1043-4666
DOI: 10.1016/j.cyto.2004.11.001

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## Abstract ## Background Liver fibrosis is characterized by the excessive accumulation of extracellular matrix (ECM). Recent advances in the knowledge about the cellular, molecular and genetic aspects of fibrosis have opened a new era of research on liver cirrhosis. A transcription factor, Sp1, o