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Lack of TP53 and FMS gene mutations in children with myelodysplastic syndrome

✍ Scribed by Biljana Jekic; Ivana Novakovic; Ljiljana Lukovic; Milos Kuzmanovic; Branka Popovic; Jelena Milasin; Gordana Bunjevacki; Tatjana Damnjanovic; Suzana Cvjeticanin; Vera Bunjevacki


Book ID
113512861
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
99 KB
Volume
166
Category
Article
ISSN
0165-4608

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New recurrent deletions in the PPARΞ³ and
✍ CΓ‘ssia G.T. Silveira; FΓ‘bio M. Oliveira; Elvis T. Valera; Maura R.V. Ikoma; Tama πŸ“‚ Article πŸ“… 2009 πŸ› Elsevier Science 🌐 English βš– 731 KB

Myelodysplastic syndrome (MDS) is a rare hematological malignancy in children. It was performed FISH analysis in 19 pediatric MDS patients to investigate deletions involving the PPARΞ³ and TP53 genes. Significant losses in the PPARΞ³ gene and deletions in the tumor suppressor gene TP53 were observed i