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Lack of Socs2 Expression Causes the High-Growth Phenotype in Mice

✍ Scribed by Simon Horvat; Juan F. Medrano

Book ID
115615351
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
164 KB
Volume
72
Category
Article
ISSN
0888-7543

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## Abstract Over‐expression of human FGF‐2 cDNA linked to the phosphoglycerate kinase promoter in transgenic (TgFGF2) mice resulted in a dwarf mouse with premature closure of the growth plate and shortening of bone length. This study was designed to further characterize bone structure and remodelin