Lack of p73 mutations and late occurrence of p73 allelic deletions in melanoma tissues and cell lines

Lack of phospholipase A2 mutations in ne

Lack of phospholipase A2 mutations in neuroblastoma, melanoma and colon-cancer cell lines

✍ Frank G. Haluska; Carol Thiele; Alisa Goldstein; Hensin Tsao; Eric P. Benoit; Da 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 61 KB 👁 2 views

A candidate murine tumor-suppressor gene, Mom1, has been identified as the secretory phospholipase A2 (GDB nomenclature: PLA2G2A) gene. Evidence suggests that PLA2G2A functions as a tumor-suppressor because mice lacking PLA2G2A expression demonstrate increased colonic polyposis. The human homologue