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Lack of mutations of the adenomatous polyposis coli gene in oesophageal and gastric carcinomas

✍ Scribed by S. Ogasawara; C. Maesawa; G. Tamura; R. Satodate


Book ID
105057615
Publisher
Springer
Year
1994
Tongue
English
Weight
872 KB
Volume
424
Category
Article
ISSN
1432-2307

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πŸ“œ SIMILAR VOLUMES


Lack of mutations of the adenomatous pol
✍ S. Ogasawara; C. Maesawa; G. Tamura; R. Satodate πŸ“‚ Article πŸ“… 1994 πŸ› Springer 🌐 English βš– 872 KB

The adenomatous polyposis coli (APC) gene is the target of the loss of chromosome 5q heterozygosity observed frequently in gastrointestinal tract carcinomas and is inactivated in these carcinomas. We screened 94 gastrointestinal tract carcinomas for APC mutations, by polymerase chain reaction single

Mutations of the APC adenomatous polypos
✍ Hiroki Nagase; Yusuke Nakamura πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 823 KB

Several investigators have reported germline mutations of the APC gene in patients with familial adenomatous polyposis (FAP) as well as somatic mutations in tumors developed in digestive organs (stomach, pancreas, colon, and rectum). Those results provide evidence that inactivation of the APC gene p

Mutation analysis of the adenomatous pol
✍ Marie Luise Bisgaard; RASMUS S. Ripa; Steffen BΓΌlow πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 26 KB πŸ‘ 2 views

## Development of one hundred or more adenomas in the colon and rectum is diagnostic for the dominantly inherited, autosomal disease Familial Adenomatous Polyposis (FAP). It is possible to identify a mutation in the Adenomatous Polyposis Coli (APC) gene in approximately 80% of the patients, and alm

Familial adenomatous polyposis coli: Fiv
✍ Maria I. Scarano; Marina De Rosa; Luigi Panariello; Nicola Carlomagno; Gabriele πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 74 KB πŸ‘ 2 views

## Germline mutations within the adenomatous polyposis coli (APC ) gene, a tumor suppressor gene, are responsible for most cases of familial adenomatous polyposis (FAP), an autosomal dominantly inherited predisposition to colorectal cancer. To date, more than 300 germ-line causative mutations with