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Lack of modulation by phenobarbital of cyclic AMP levels or protein kinase A activity in rat primary hepatocytes

โœ Scribed by Nancy B Beck; Curtis J Omiecinski


Book ID
113994524
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
293 KB
Volume
58
Category
Article
ISSN
0006-2952

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Modulation of protein kinase C by taurol
โœ Ulrich Beuers; Irmelin Probst; Carol Soroka; James L. Boyer; Gerd-A. Kullak-Ubli ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 331 KB ๐Ÿ‘ 1 views

The protein kinase C (PKC) family of isoenzymes plays a key role in the regulation of hepatocellular secretion. The hydrophobic and cholestatic bile acid, taurolithocholic acid (TLCA), acts as a potent Ca++ agonist in isolated hepatocytes. However, its effect on PKC isoforms has not been elucidated.