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Lack of linkage between the corticotropin-releasing hormone (CRH) gene and bipolar affective disorder

✍ Scribed by Stratakis, C A; Sarlis, N J; Berrettini, W H; Badner, J A; Chrousos, G P; Gershon, E S; Detera-Wadleigh, S D

Book ID
110058797
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
52 KB
Volume
2
Category
Article
ISSN
1359-4184

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The serotonin transporter (5HTT) gene appears to be of particular interest as 5HTT is the selective site of action of selective serotonin reuptake inhibitors (SSRIs) that successfully treat bipolar depression (BP). The 5HTT gene is located on chromosome 17q11.1-q12 and has a 44 bp deletion/insertion