✦ LIBER ✦

Lack of guanylate cyclase C (GC-C) leads to reduction of adenoma formation in murine model of intestinal cancer

✍ Scribed by Mann, Elizabeth A.; Steinbrecher, Kris A.; Witte, David; Cohen, Mitchell B.; Giannella, Ralph A.

Book ID: 124115753
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 222 KB
Volume: 120
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(08)81478-3

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Mo2029 Extracellular Cyclic GMP (cGMP),

Mo2029 Extracellular Cyclic GMP (cGMP), the Downstream Mediator Released in Response to Linaclotide-Induced Activation of Guanylate Cyclase-C (GC-C), Reduces Excitability of Murine and Human Dorsal Root Ganglion (DRG) Neurons

✍ Castro, Joel; Rychkov, Grigori Y.; Ghetti, Andrea; Harrington, Andrea M.; Kurtz, 📂 Article 📅 2014 🏛 Elsevier Science 🌐 English ⚖ 166 KB

Lack of guanylyl cyclase C, the receptor

Lack of guanylyl cyclase C, the receptor for Escherichia coli heat-stable enterotoxin, results in reduced polyp formation and increased apoptosis in the multiple intestinal neoplasia (Min) mouse model

✍ Elizabeth A. Mann; Kris A. Steinbrecher; Carmen Stroup; David P. Witte; Mitchell 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 363 KB

## Abstract Guanylyl cyclase C (GC‐C), a transmembrane receptor for bacterial heat‐stable enterotoxin and the mammalian peptides guanylin and uroguanylin, mediates intestinal ion secretion and affects intestinal cell growth via cyclic GMP signaling. In intestinal tumors, GC‐C expression is maintain