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Lack of evidence for inhibition of angiogenesis as a central mechanism of the antiarthritic effect of methotrexate

✍ Scribed by Christoph Fiehn; Andreas Wunder; Stefan Krienke; Regina Max; Anthony D. Ho; Thomas Moehler

Publisher
Springer
Year
2003
Tongue
English
Weight
358 KB
Volume
25
Category
Article
ISSN
0172-8172

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The effects of 1␣-hydroxyvitamin D 3 [1␣(OH)D 3 ] and 1,25dihydroxyvitamin D 3 [1,25(OH) 2 D 3 ] on the incidence of colon tumors induced by azoxymethane and on the labeling index and angiogenesis of colon tumors were investigated in Wistar rats. Rats received 10 weekly injections of 7.4 mg/kg body