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Lack of Evidence for Association of the Serotonin Transporter Gene SLC6A4 with Autism

โœ Scribed by Nicolas Ramoz; Jennifer G. Reichert; Thomas E. Corwin; Christopher J. Smith; Jeremy M. Silverman; Eric Hollander; Joseph D. Buxbaum


Book ID
119197100
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
192 KB
Volume
60
Category
Article
ISSN
0006-3223

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The serotonin transporter (5HTT) gene appears to be of particular interest as 5HTT is the selective site of action of selective serotonin reuptake inhibitors (SSRIs) that successfully treat bipolar depression (BP). The 5HTT gene is located on chromosome 17q11.1-q12 and has a 44 bp deletion/insertion