Lack of evidence for activation of a serum factor in protease-induced differentiation of mouse erythroleukemia cells
β Scribed by Barbara M. Scher; William Scher; Samuel Waxman
- Book ID
- 112799393
- Publisher
- Society for In Vitro Biology
- Year
- 1985
- Tongue
- English
- Weight
- 547 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1475-2689
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The in vivo differentiation-inducing activity of a purified human erythroid differentiation factor (EDF) toward mouse erythroleukemic cells (MEL cells) was examined. BDF, mice with diffusion chambers implanted in the peritoneal cavity were treated with continuous i.p. administration of EDF. MEL cell
## Abstract Eukaryotic translation initiation factor 5A (eIF5A) has a unique character: the presence of an unusual amino acid, hypusine, which is formed by postβtranslational modifications. Even before the identification of hypusination in eIF5A, the correlation between hypusine formation and prote