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Lack of effect of islet amyloid polypeptide on hepatic glucose output in the in situ-perfused rat liver

✍ Scribed by Susumu Nishimura; Tokio Sanke; Kazuo Machida; Hiroto Bessho; Tadashi Hanabusa; Kazuhiko Nakai; Kishio Nanjo

Book ID
116030523
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
531 KB
Volume
41
Category
Article
ISSN
1532-8600

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Effects of islet amyloid polypeptide on
Effects of islet amyloid polypeptide on hepatic insulin resistance and glucose production in the isolated perfused rat liver
✍ M. Roden; K. Liener; C. FΓΌrnsinn; P. Nowotny; U. Hollenstein; H. Vierhapper; W. πŸ“‚ Article πŸ“… 1992 πŸ› Springer 🌐 English βš– 523 KB

The impact of (pancreatic) islet amyloid polypeptide on glucose metabolism and insulin sensitivity was examined in isolated rat livers perfused in a non-recirculating system. Continuous infusion of 10-7mol/1 islet amyloid polypeptide affected neither basal nor glucagon (10-9 mol/1)stimulated glucose