𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Lack of Effect of Cholesterol Esterase Inhibitor CVT-1 on Cholesterol Absorption and LDL cholesterol in Humans

✍ Scribed by Matthew S. Bosner; Andrew A. Wolff; Richard E. Ostlund


Book ID
110255591
Publisher
Springer US
Year
1999
Tongue
English
Weight
93 KB
Volume
13
Category
Article
ISSN
0920-3206

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Effect of the ACAT inhibitor CI-976 on p
✍ Brian R. Krause; Richard F. Bousley; Karen A. Kieft; Richard L. Stanfield πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science 🌐 English βš– 724 KB

The overall objective of the present study was to determine if the ACAT inhibitor CI-976 can lower plasma cholesterol in hamsters fed zero or low, "human-like" levels of cholesterol. With a purified diet containing zero dietary cholesterol, CI-976 significantly lowered VLDL cholesterol (VLDL-C), but

The tolerability, pharmacokinetics and l
✍ R. W. Peck; R. Wiggs; J. Posner πŸ“‚ Article πŸ“… 1995 πŸ› Springer 🌐 English βš– 657 KB

2 dimethylpropyl) phenyl)ethyl)phenyl)urea) is an inhibitor of human microsomal AcylCoA: Cholesterol acyltransferase (ACAT) with an ICs0 of 10.2 rig' m1-1 (23 nM). It is poorly absorbed but 5 mg. kg-1-daycompletely abolishes the rise in plasma cholesterol in cholesterol-fed rats. In this study, tw