Lack of correlation between histone H4 acetylation and transcription during the Physarum cell cycle
✍ Scribed by Loidl, P.; Loidl, A.; Puschendorf, B.; Gröbner, P.
- Book ID
- 109732179
- Publisher
- Nature Publishing Group
- Year
- 1983
- Tongue
- English
- Weight
- 459 KB
- Volume
- 305
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/305446a0
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## Abstract The CCAAT displacement protein (CDP‐cut/CUTL1/cux) performs a key proliferation‐related function as the DNA binding subunit of the cell cycle controlled HiNF‐D complex. HiNF‐D interacts with all five classes (H1, H2A, H2B, H3, and H4) of the cell‐cycle dependent histone genes, which are
Cell cycle control of histone H4 gene transcription is mediated by the multipartite promoter domain H4-Site II, which supports transcriptional activation at the G1/S phase transition and modulates basal H4 gene transcription. Proliferation-specific transcription is determined by the integrated activ