๐”– Bobbio Scriptorium
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Lack of cold sensitivity in hyperkalemic periodic paralysis

โœ Scribed by Dr. S. H. Subramony; Abelardo S. Wee; Shri K. Mishra

Book ID
102537588
Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
382 KB
Volume
9
Category
Article
ISSN
0148-639X

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โœฆ Synopsis

The nosologic distinction between paramyotonia congenita and hyperkalemic periodic paralysis is somewhat blurred. Muscle membrane inexcitability induced by cooling seems to be characteristic of paramyotonia congenita. The effect of cooling on the maximal compound muscle action potential (CMAP) in patients with paramyotonia congenita was compared to that in patients with hyperkalemic periodic paralysis. Diminution in CMAP amplitude and area, which was observed in paramyotonia congenita, did not occur in hyperkalemic periodic paralysis. We suggest that this effect of cooling on the CMAP can be utilized in the differentiation of these two syndromes.

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