Lack of association between outcome measures of nerve regeneration

✍ Scribed by Catherine A. Munro; John P. Szalai; Susan E. Mackinnon; Rajiv Midha

• Book ID: 101251589
• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 77 KB
• Volume: 21
• Category: Article
• ISSN: 0148-639X
• DOI: 10.1002/(sici)1097-4598(199808)21:8<1095::aid-mus20>3.0.co;2-s

✦ Synopsis

Studies of nerve regeneration in rodents utilize at least one of three classes of outcome measures: electrophysiology, morphometry, and functional tests. The assumption that these measures are correlated was tested utilizing a data set of 16 variables. Significant correlations (Spearman's rho, P ഛ 0.05) were found within variable classes; however, none were found between classes. The three commonly utilized outcome measures do not measure the same phenomenon but rather discrete aspects of nerve regeneration.