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Lack of a correlation between p53 protein expression and radiation response in human tumor primary cultures

✍ Scribed by Nadia Zaffaroni; Elvira Benini; Daniela Gornati; Alessandra Bearzatto; Rosella Silvestrini


Book ID
112212684
Publisher
AlphaMed Press
Year
1995
Tongue
English
Weight
637 KB
Volume
13
Category
Article
ISSN
1066-5099

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To assess the potential relationship between p53 and p16 proteins in the cellular response to stress, we have examined the levels of these proteins in a series of human tumor cell lines after treatment with either ionizing radiation or hyperthermia. We found that cells with abnormal radiationinduced