Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice
โ Scribed by Atsushi Fukai; Satoru Kamekura; Daichi Chikazu; Takumi Nakagawa; Makoto Hirata; Taku Saito; Yoko Hosaka; Toshiyuki Ikeda; Kozo Nakamura; Ung-il Chung; Hiroshi Kawaguchi
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 481 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective Recent studies have implicated products of cyclooxygenase 2 (COXโ2) in not only induction but also resolution of the inflammatory response; however, the contribution of COXโ2 products to the in vivo response to infection is unknown. The aim of this study was to determine t
## Abstract ## Objective To determine whether oral glucosamine alleviates cartilage degradation in an animal model of osteoarthritis (OA). ## Methods The effect of 8 weeks of daily oral glucosamine hydrochloride on degeneration of articular cartilage was evaluated in rabbits in which anterior cr