Lac Repressor Binding to DNA not containing the Lac Operator and to Synthetic Poly dAT

Combined procedure of distance geometry

Combined procedure of distance geometry and restrained molecular dynamics techniques for protein structure determination from nuclear magnetic resonance data: Application to the DNA binding domain of lac repressor from Escherichia coli

✍ J. de Vlieg; R. M. Scheek; W. F. van Gunsteren; H. J. C. Berendsen; R. Kaptein; 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 English ⚖ 981 KB

The technique of two-dimensional nuclear magnetic resonance (2D-NMR) has recently assumed an active role in obtaining information on structures of polypeptides, small proteins, sugars, and DNA fragments in solution. In order to generate spatial structures from the atom-atom distance information obta