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Laboratory diagnosis of japanese encephalitis using monoclonal antibodies and correlation of findings with the outcome

✍ Scribed by Dr. V. Ravi; S. Vanajakshi; Anke Gowda; A. Chandramuki


Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
285 KB
Volume
29
Category
Article
ISSN
0146-6615

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✦ Synopsis


Detection of virus, viral antigen, and class-specific antibody was carried out in cerebrospinal fluid (CSF) and sera of 27 children with Japanese encephalitis. The diagnosis could be confirmed in 78.57% of cases (22/27) by demonstration of virus-specific IgM in CSF (151221, viral antigen in CSF (5/22), or by virus isolation (2122). Absence of virus specific IgM in CSF was associated with a fatal outcome (P= 0.05).


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