Classifying variants of CDKN2A using com
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Peter J. Miller; Sekhar Duraisamy; Joan A. Newell; Philip A. Chan; Mark M. Tie;
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Article
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2011
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John Wiley and Sons
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English
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Variants in the CDKN2A tumor suppressor are associated with Familial Melanoma (FM), although for many variants the linkage is weak. The effects of missense variants on protein function and pathogenicity are often unclear. Multiple methods (e.g., laboratory, computational, epidemiological) have been