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Labeling of [18F]flumazenil via instant fluorination, a new nucleophilic fluorination method

✍ Scribed by A. D. Windhorst; R. P. Klok; C. L. Koolen; G. W. M. Visser; J. D. M. Herscheid


Book ID
112132786
Publisher
John Wiley and Sons
Year
2001
Tongue
French
Weight
165 KB
Volume
44
Category
Article
ISSN
0022-2135

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Preparation of N.C.A. [17-18F]-fluorohep
✍ Heinrich Hubert Coenen; Manfred SchΓΌller; Gerhard StΓΆcklin; Bernd Klatte; Arndt πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 French βš– 445 KB

A macrocyclic aminopolyether (Kryptofix 2.2.2.) supported labelling method for the preparation of n.c.a. [17-FIfluoroheptadecanoic acid is described. The equimolar complex of potassium carbonate and the aminopolyether is used to provide nucleophilicity in a homogeneous solution of acetonitrile. Nuc