Labeled bile acids I: Synthesis of 18O-methyl hydroxy-5β-cholan-24-oates
✍ Scribed by Warren G. Anderson; Chang Yon Byon; Charles R. Eck; Marcel Gut
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- French
- Weight
- 261 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
The i n c o r p o r a t i o n o f l 8 0 i n t o t h e 3-hydroxyl o f b i l e acids has been accomplished by h y d r o l y s i s o f t h e a c e t a l corresponding t o t h e 3-OX0 b i l e a c i d w i t h H2l80, f o l l o w e d by hydride r e d u c t i o n o f t h e ketone t o t h e l a b e l e d hydroxyl f u n c t i o n .
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