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Label-Free Detection of Protein–Protein Interactions on Biochips

✍ Scribed by Woon-Seok Yeo; Dal-Hee Min; Robert W. Hsieh; Geoffrey L. Greene; Milan Mrksich

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
139 KB
Volume
117
Category
Article
ISSN
0044-8249

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## Abstract The adsorption of the protein avidin from hen egg white on patterns of silicon dioxide and platinum surfaces on a microchip and the use of fluorescent microscopy to detect binding of biotin are described. A silicon dioxide microchip was formed using plasma‐enhanced chemical vapor deposi