✦ LIBER ✦

L-Tryptophan and prolactin release: Evidence for interaction between 5-HT1 and 5-HT2 receptors

✍ Scribed by E. M. Charig; I. M. Anderson; J. M. Robinson Sen; D. J. Nutt; P. J. Cowen

Publisher: John Wiley and Sons
Year: 1986
Tongue: English
Weight: 429 KB
Volume: 1
Category: Article
ISSN: 0885-6222
DOI: 10.1002/hup.470010206

No coin nor oath required. For personal study only.

✦ Synopsis

The effects of the selective 5-HT2 receptor antagonist, ritanserin, on the growth hormone (GH) and prolactin (PRL) responses to intravenous L-tryptophan (LTP) were assessed in 8 normal volunteers. Administration of ritanserin (40 mg orally) prior to infusion of LTP (5 g) significantly enhanced the PRL responses but not those of GH. The results are consistent with previous proposals that the endocrine responses to LTP are mediated by 5-HT1 rather than 5-HT2 receptors and also suggest that 5-HT2 receptor antagonists may increase certain 5-HT, mediated responses in the human brain.

📜 SIMILAR VOLUMES

Regulation of striatal dopamine release

Regulation of striatal dopamine release through 5-HT1 and 5-HT2 receptors

✍ Ngan-Koon Ng; How-Sung Lee; Peter T.-H. Wong 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 173 KB 👁 1 views

Dopamine (DA) release in the striatum is regulated by 5-hydroxytryptamine (5-HT, serotonin) through putative heteroreceptors. However, the effect of 5-HT is controversial. The present study investigated the effects of different 5-HT receptor ligands on DA release in the rat striatum by using in vivo

ChemInform Abstract: Synthesis and Bindi

ChemInform Abstract: Synthesis and Binding Affinities for 5-HT1A, 5-HT2A and 5-HT2C Receptors of a Series of 1- and 2-(4-Arylpiperazinylalkyl)-4-(benzoyl)-1,2,3-triazole Derivatives.

✍ Giuseppe Caliendo; Ferdinando Fiorino; Paolo Grieco; Elisa Perissutti; Vincenzo 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

5-HT1A, 5-HT2, and GABAB receptors inter

5-HT1A, 5-HT2, and GABAB receptors interact to modulate neurotransmitter release probability in layer 2/3 somatosensory rat cortex as evaluated by the paired pulse protocol

✍ José L. Torres-Escalante; Jaime A. Barral; María D. Ibarra-Villa; Azucena Pérez- 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 231 KB

## Abstract Activation of γ‐aminobutyric acid B (GABA~B~) and 5‐hydroxytryptamine (5‐HT) receptors produces presynaptic inhibition at glutamatergic terminals in the rat neocortex. To evaluate interactions between these metabotropic receptors, field potentials were recorded in layer 2/3 of somatosen

5-HT1A, 5-HT2, and GABAB receptors inter

5-HT1A, 5-HT2, and GABAB receptors interact to modulate neurotransmitter release probability in layer 2/3 somatosensory rat cortex as evaluated by the paired pulse protocol

✍ José L. Torres-Escalante; Jaime A. Barral; María D. Ibarra-Villa; Azucena Pérez- 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 41 KB

The authors mistakenly stated that all records were done in ''somato-sensory cortex'' when in fact some of the records in the report were actually done in motor cortex. Thus, ''somato-sensory cortex'' should be replaced by ''sensory-motor cortex'' throughout the piece. The authors regret this mistak

Synthesis of New Hexahydro- and Octahydr

Synthesis of New Hexahydro- and Octahydropyrido[1,2-c]pyrimidine Derivatives with an Arylpiperazine Moiety as Ligands for 5-HT1A and 5-HT2A Receptors. Part 2.

✍ F. Herold; J. Kleps; G. Nowak; M. Maj 📂 Article 📅 2004 🏛 John Wiley and Sons ⚖ 82 KB 👁 1 views

ChemInform Abstract: Quinolizidinyl Deri

ChemInform Abstract: Quinolizidinyl Derivatives of 2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxylic Acid and 1-Homolupinanoyl Benzimidazolones as Ligands for 5-HT3 and 5-HT4 Receptors.

✍ Anna Sparatore; Alfredo Cagnotto; Fabio Sparatore 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views