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l-Kynurenine-induced apoptosis in human NK cells is mediated by reactive oxygen species

✍ Scribed by Hyunkeun Song; Hyunjin Park; Yeong-Seok Kim; Kwang Dong Kim; Hyun-Kyung Lee; Dae-Ho Cho; Jae-Wook Yang; Dae Young Hur


Book ID
116576866
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
852 KB
Volume
11
Category
Article
ISSN
1567-5769

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## Abstract There is an emerging evidence that plumbagin (5‐hydroxy‐2‐methyl‐1, 4‐naphthoquinone) may have potential as a chemotherapeutic agent. However, the growth inhibitory mechanisms of plumbagin have remained unexplored. The aim of the study was to determine whether plumbagin‐induced cell dea