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l-DOPA administration to neonate chicks: Effects on behavior and levels of brain biogenic amines

โœ Scribed by J. P. Hanig; J. Seifter


Book ID
112700723
Publisher
Springer
Year
1971
Tongue
English
Weight
259 KB
Volume
27
Category
Article
ISSN
1420-682X

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Administration of L-dopa (L-3,4-dihydroxyphenylalanine) (200 mg/kg p.o.) to rats produced elevated plasma and muscle concentrations of both L-dopa and 3-O-methyldopa (3-OMD). This effect was potentiated by simultaneous administration of carbidopa (25 mg/kg p.o.). Both L-dopa and 3-OMD accumulated in