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l-Carnitine delays the killing of cultured hepatocytes by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

✍ Scribed by Jack W. Snyder; Marlene E. Kyle; Thomas N. Ferraro


Book ID
115708353
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
794 KB
Volume
276
Category
Article
ISSN
0003-9861

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Primary cultures of mouse astrocytes were treated with both the monoamine oxidase (MAO) A inhibitor, clorgyline, and the MA0 B inhibitor, deprenyl, prior to the addition of the neurotoxicant 1 -methyl-4-phenyl-l,2,3,6-tetrahydropyridine (MPTP). Production of the 1-methyl-4-phenylpyridinium (MPP+) to