## Abstract The conformation of oligopeptides with hydrophobic side chains, Nps‐(L‐Leu‐L‐Leu‐L‐Ala)~__n__~‐OEt and Nps‐(L‐Met‐L‐Met‐L‐Leu)~__n__~‐OEt(__n__ = 1–6), in the solid state, obtained either by evaporation of the solvent or by precipitation with diethyl ether from a 1,1,1,3,3,3‐hexafluorop
✦ LIBER ✦
l-Alanyl-l-Leucyl-l-Tyrosyl-l-Leucyl-l-Valin
✍ Scribed by Zahn, Helmut ;La France, Norman H.
- Book ID
- 102363814
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1960
- Weight
- 495 KB
- Volume
- 630
- Category
- Article
- ISSN
- 0074-4617
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Das in der Phenylalaninkette des Insulins vorkommende Pentapeptid l‐Alanyl‐l‐leucyl‐l‐tyrosyl‐l‐leucyl‐l‐valin wurde aus Carbobenzoxy‐l‐alanyl‐l‐leucin und l‐Tyrosyl‐l‐leucyl‐l‐valin synthetisiert und sein säurehydrolytischer und enzymatischer Abbau untersucht.
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Two series of peptides with hydrophobic side chains, Nps-(L-Leu-L-Leu-L-Ala),OEt and Nps-(L-Met-L-Met-L-Leu),-OEt (n = 1-61. were synthesized by the fragment condensation method using dicyclohexylcarbodiimide in the presence of N-hydroxysuccinimide. The tripeptide fragments were prepared stepwise by
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