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Kv1.3 potassium channels as a therapeutic target in multiple sclerosis

✍ Scribed by Rangaraju, Srikant; Chi, Victor; Pennington, Michael W; Chandy, K George


Book ID
118049964
Publisher
Informa plc
Year
2009
Tongue
English
Weight
873 KB
Volume
13
Category
Article
ISSN
1472-8222

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The lymphocyte potassium channels Kv1.3
✍ Jenny Lam; Heike Wulff πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 213 KB

## Abstract The voltage‐gated Kv1.3 and the calcium‐activated KCa3.1 potassium channel modulate many calcium‐dependent cellular processes in immune cells, including T‐cell activation and proliferation and have therefore been proposed as novel therapeutic targets for immunomodulation. Kv1.3 is highl