✦ LIBER ✦

KSTAGE: An interactive computer program for designing phase II clinical trials using predictive probability

✍ Scribed by E.Neely Atkinson; Barry W. Brown; Jay Herson

Publisher: Elsevier Science
Year: 1982
Tongue: English
Weight: 450 KB
Volume: 15
Category: Article
ISSN: 0010-4809
DOI: 10.1016/0010-4809(82)90057-x

No coin nor oath required. For personal study only.

✦ Synopsis

Early termination of clinical trials is advisable if initial evidence indicates the treatment under study is ineffective. Predictive probability methods permit the construction of multistage studies that allow for early termination while still controlling overall false-positive (declare an ineffective treatment effective) and false-negative (declare an effective treatment ineffective) error rates. An interactive computer program known as KSTAGE has been developed that aids the researcher in designing such studies.

I. USE

📜 SIMILAR VOLUMES

A Microcomputer Program for the Design a

A Microcomputer Program for the Design and Analysis of Phase II Cancer Clinical Trials with Two Group Sequential Methods, the Sequential Probability Ratio Test, and the Triangular Test

✍ E. Bellissant; J. Benichou; Cl. Chastang 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 470 KB

We developed an interactive and menu-driven computer program to help investigators design and analyze phase II cancer clinical trials with a group sequential method, namely the sequential probability ratio test or the triangular test. Based on the values selected for the parameters of the trial, the