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Kruppel-like factor 5 modulates p53-independent apoptosis through Pim1 survival kinase in cancer cells

✍ Scribed by Zhao, Y; Hamza, M S; Leong, H S; Lim, C-B; Pan, Y-F; Cheung, E; Soo, K-C; Iyer, N G

Book ID
110072617
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
339 KB
Volume
27
Category
Article
ISSN
0950-9232

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## BACKGROUND. Apoptosis is induced by various anticancer agents or radiation through the tumor suppressor gene p53-dependent pathway and is also induced by other factors, including transforming growth factor-PI (TGF-0,). In this study, the authors investigated whether TGF-0, would induce apoptosi