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Kringle-2 domain of the tissue-type plasminogen activator : 1H-NMR assignments and secondary structure

✍ Scribed by In-Ja L. BYEON; Robert F. KELLEY; Miguel LLINÁS


Book ID
115128509
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
1004 KB
Volume
197
Category
Article
ISSN
1432-1327

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The growth factor receptor-bound protein-2 (Grb2) is an adaptor protein that mediates signal transduction pathways. Chemical shift assignments were obtained for the SH2 domain of Grb2 by heteronuclear NMR spectroscopy, employing the uniformly 13C-/15N-enriched protein as well as the protein containi