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KRAS status as a predictor of response to EGFR inhibitors in mCRC

✍ Scribed by Jame Abraham

Book ID
118628212
Publisher
Frontline Medical Communications, Inc.
Year
2008
Tongue
English
Weight
112 KB
Volume
5
Category
Article
ISSN
1548-5315

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## Abstract __KRAS__ mutations are a strong predictive marker of resistance to anti‐epidermal growth factor receptor (EGFR) antibodies in advanced colorectal cancer (CRC) but only a subset of wild‐type (WT) __KRAS__ patients are responders, suggesting the existence of additional markers of resistan