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Knockdown of Thrombomodulin Enhances HCC Cell Migration through Increase of ZEB1 and Decrease of E-cadherin Gene Expression

✍ Scribed by Ming-Te Huang; Po-Li Wei; Jun-Jen Liu; Der-Zen Liu; Huang Huey-Chun; Jane An; Cheng-Chia Wu; Chih-Hsiung Wu; Yuan-Soon Ho; Yi-Yuan Yang; Yu-Jia Chang

Book ID: 111773678
Publisher: Springer
Year: 2010
Tongue: English
Weight: 500 KB
Volume: 17
Category: Article
ISSN: 1068-9265
DOI: 10.1245/s10434-010-1163-4

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## Abstract We investigated the effects of overexpression of the tuberous sclerosis‐1 and ‐2 (__TSC1/2__) gene products (hamartin and tuberin, respectively) in the human kidney epithelial cell line 293 with an inducible expression system. As we had observed previously in fibroblasts, 293 cells over