𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth

✍ Scribed by Melissa L. Fishel; Ying He; April M. Reed; Helen Chin-Sinex; Gary D. Hutchins; Marc S. Mendonca; Mark R. Kelley

Book ID
113567910
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
1005 KB
Volume
7
Category
Article
ISSN
1568-7864

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The Ape-1/Ref-1 redox antagonist E3330 i
The Ape-1/Ref-1 redox antagonist E3330 inhibits the growth of tumor endothelium and endothelial progenitor cells: Therapeutic implications in tumor angiogenesis
✍ Gang-Ming Zou; Collins Karikari; Yasuaki Kabe; Hiroshi Handa; Robert A. Anders; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 314 KB

## Abstract The apurinic/apyrimidinic endonuclease 1/redox factor‐1 (Ape‐1/Ref‐1) is a multi‐functional protein, involved in DNA repair and the activation of redox‐sensitive transcription factors. The Ape‐1/Ref‐1 redox domain acts as a cytoprotective element in normal endothelial cells, mitigating